FTA-200, FTA-ABS, and TPI Tests in Serodiagnosis of Syphilis

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Comparison of the VDRL slide, TPI, and FTA-ABS tests in experimental syphilis in rabbits.

The first serological test for syphilis, developed by Wassermann, Neisser, and Bruck (1906), was a complement-fixation test for reagin activity. Many tests for reagin activity have been developed since then, including the Kline, Kahn, Hinton, Kolmer, Mazzini, and VDRL slide tests. However, none of these is absolutely specific for syphilis. The VDRL slide test (Harris, Rosenberg, and Riedel, 194...

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Absorbed fluorescent treponemal antibody (FTA-ABS) test. Comparison with the FTA-200 and TPI tests on 1,056 problem sera.

Deacon and Hunter (1962) have shown that the fluorescent treponemal antibody (FTA) test detects two separate antibodies in syphilitic sera. One, a group antibody, reacts with other treponemes, such as the Reiter organism, Treponema microdentium, and Treponema zuelzerae, as well as with Treponema pallidum, presumably because of an antigen shared in common by these organisms. Removal of group ant...

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Treponema pallidum haemagglutination test for syphilis. Comparison with TPI and FTA-ABS tests.

The Treponema pallidum haemagglutination (TPHA) test, the latest to be developed in the group of specific tests for syphilis, has been described by Tomizawa and Kasamatsu (1966), Rathlev (1967), Tomizawa, Kasamatsu, and Yamaya (1969), and Tringali (1970.) An automated microhaemagglutination technique, the AMHA-Tp test, has been evaluated by Cox, Logan, and Norins (1969) and Logan and Cox (1970)...

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Treponema pallidum haemagglutination test for yaws. Comparison with the TPI and FTA-ABS tests.

Similar antibodies are produced in the serum of patients infected with the pathogenic treponemes T. pallidum and T. pertenue, and for this reason sera from persons with syphilis or yaws react similarly in the conventional tests for syphilis and in the Treponema pallidum immobilization (TPI) and fluorescent treponemal antibody absorption (FTAABS) tests. In the TPI and FTA-ABS tests T. pallidum i...

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The FTA-ABS test for syphilis. Performance in 1,033 patients.

During the 20th century, screening tests using nontreponemal lipoidal antigens have evolved from the old Wassermann test to such excellent ones as the VDRL and Kahn flocculation tests and the Kolmer complement-fixation test. These tests are easily performed in small laboratories and are almost invariably reactive in patients who have any form of active syphilis other than primary syphilis. Alth...

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ژورنال

عنوان ژورنال: Public Health Reports (1896-1970)

سال: 1965

ISSN: 0094-6214

DOI: 10.2307/4592540